Diabetes drugs prediction web server and database
Blog #6 Hi everyone. There is an extremely useful database called "DIA-DB: A Database and Web Server for the Prediction of Diabetes Drugs," which is recently reported in the American Chemical Society's Journal of Chemical Information and Modeling (JCIM). This is the first and open access web server for the prediction of diabetes drugs. It does not require any registrations and the user receives an email with a comprehensive report containing the prediction results. It employs two distinct approaches: a) 3D shape-based similarity approach for comparison of antidiabetic approved and experimental compounds. b) inverse virtual screening of the input molecules chosen by users: It performs large-scale inverse docking (using Autodock Vina) on a collection of proteins involved in diabetes with the goal of identifying a query compound's possible target. Researchers may also use the DIA-DB to find out whether any of the already-approved or experimental compounds are included ...